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Most caregivers who test their pets’ blood glucose levels use human glucometers. These two documents  compare the features of various glucometers and link to the Internet sites for the manufacturers. Ease of use ratings  and more specifics can be found at the link below for all major US brands. Some brands of glucometers have a switch or set-up option, allowing the user to perform testing using either mmol/L (millimoles/liter-world standard measuring unit) or mg/dL (milligrams/deciliter-traditional measuring unit) measurements.  Making sure your meter is set to measure blood glucose in the common form for your country can avoid possible misinterpretation of readings.  See glucometer units of measure for a list of various countries and the standards used in them.
Buying a Glucometer and Test StripsEdit
You can buy a glucometer at a brick-and-mortar or Internet pharmacy that sells diabetic supplies. You can expect to pay $25 to $50 for a glucometer in the US. However, manufacturers often have rebate certificates that can make the meter free. Check the advertising supplements in your newspaper for pharmacies that have rebate offers or “buy the strips, get the meter free” deals. Internet pharmacies also often offer similar rebates and deals.
It is the strips, not the meters, that are the pricey part of hometesting blood glucose. Consider checking the price and eBay availability of strips before you decide on a meter. However, even though the strips may be pricey, the cost and stress of performing blood glucose tests at home is far less than at the vet. Also, testing before every insulin shot protects your pet from an accidental overdose of insulin (hypoglycemia) and can provide valuable analytical information for you and your vet to make dosing decisions.
Choosing the best kindEdit
Factors to consider for choosing your own include:
- Blood drop size
- Ease of use
- Precision (how repeatable are the results)
- Accuracy (how correct are the results)
- Error behavior (can the meter give a bad reading?)
- Data upload ability (for recording and plotting readings over time)
Dogs are less resilient to the effects of hyperglycemia than cats, and therefore canine caregivers may need to be more exacting about the accuracy of their readings. Cats may be harder to get large blood drops from painlessly, so feline caregivers may be more concerned about the size of blood drop required, and the error behavior.
For any pet, it is important to get a meter that takes only a small amount of blood and that has “sipping” strips that automatically draw the blood up into the strip. Sipping (aka "capillary action") strips are much easier to use for pets and use less blood. When a meter requires less blood, the process is easier and quicker.
Some meters require a blood drop of one microliter or less: the size of a pinhead. A couple use only 1/3 of a microliter. For comparison's sake, one microliter equals 0.001 milliliter or 1 cubic centimeter; it is about the size of a ball-point pen tip. . The link below gives the amount of blood sample needed for all glucometers currently sold in the US in graph form 
Some meters can give a false reading when the blood sample is not full. Others will refuse to give any reading until it is full. Some will allow the addition of blood to the sample to be tested without generating an error message while others won't.
Many meters have additional “bells and whistles” such as multiple daily alarms for curving and the ability to upload readings to an electronic format (such as a spreadsheet) for easy logging. If you'd like to upload insulin logs, ask the retailer or the manufacturer's support line for a "data cable" for the meter -- it's often free if you ask!  Most meters on the market now have a built-in data port. 
Two more glucometers are the FreeStyle Freedom from Abbott:  Made for people, it claims to require the 0.3 microliters, the smallest blood sample of any meter on the market. And LifeScan's (Johnson & Johnson) One Touch Ultra 2  which has quite a bit of "on board" software built in to help you track blood glucose trends. It uses the OneTouch Ultra strips and promises results with a "speck" of blood in 5 seconds.
No Coding RequiredEdit
Newer meters are eliminating the "coding" process of matching the new box of test strips with the meter.  The necessary information is now part of each test strip. Bayer's Ascensia Contour and Breeze  and Abbott's Precision Xtra--for both blood glucose and blood ketone testing--no longer require coding;  Abbott's name for their system is SmartChip Technology.  Accu-Chek's Compact Plus is also a "no coding" meter. 
If you want a meter that also checks for ketones in the blood, as opposed to using Urine testing stix, the only meter currently available able to do this is Abbott's Precision Xtra. 
By using special test strips, ketone values in the blood can be known within 10 seconds.  The new strips are fully compatible with existing Precision Xtra meters.
The meter itself is more expensive than average (regular surfing for online pharmacy sales can mean buying it for about $10). The ketone test strips are about $30 for a pack of 10 individually sealed.  This meter is known as Precision Optimum/Xceed  outside of the US.
Whole Blood vs Plasma ReadingsEdit
Glucose levels in plasma (a component of blood) are generally 10-15% higher (even more after eating) than glucose measurement in whole blood.  All of our home devices actually measure the glucose content of whole blood. Most lab testing measures the glucose content of the plasma.
Many currently marketed meters automatically display their readings (through a math algorithm built into the device) as plasma equivalent, thus allowing one to better compare their meter results to those of lab testing. It's important that you know whether the meter you're using displays readings as whole blood equivalent or plasma equivalent.
Meters for animalsEdit
Some people prefer to buy animal validated meters. On the other hand, some testing  by volunteers from the FDMB found no significant difference in accuracy between the Abbott AlphaTrak and leading human glucometers, on feline blood.
Animal-specific systems are far more expensive than glucometers and test strips made for humans. A vial of 50 test strips for one model is $75. Alterations are made to the human test strips to produce a result in all but the Abbott AlphaTrak meter.
When a system appeared in 2004, the FreeStyle meter was offered with the altered strips. Those animal-validated strips are no longer available, but caregivers can purchase/use standard FreeStyle test strips in that meter. The currently offered meter for one system with animal-validated strips is the EasyGluco.  You cannot use the EasyGluco strips in the FreeStyle meter.
In March, 2006, Abbott began marketing its AlphaTrak  animal-validated glucometer. It basically operates similarly to those above, with the validation process being accomplished through obtaining blood glucose test results over a period of time from dogs and cats and validating through averages of them  as compared to Antech Laboratories' results. Over 200 dogs and 200 cats were tested to validate the AlphaTrak meter--in each group, only slightly more than 50 were diabetes patients.
In the AlphaTrak system, it's the meter which is validated; the products above validate through the test strips. Knowing that the validation was applied to the meter and not the strips, it's interesting to note that Abbott's latest glucometer for people, the FreeStyle Freedom described below, also is able to use the tiny 0.3 microliter blood sample as well. All blood testing was with venous, not capillary, blood. 
Meters made for human use are accurate in measuring blood glucose levels in animals above 80 mg/dl. At the lower ranges, the accuracy is less because of the difference in size of red blood cells (erythrocytes) between species.  Glucometers for humans were successfully used with pets long before animal-oriented meters were produced. 
You can compare the variance between your home meter and the vet's lab testing easily enough. Take your meter with you when vet blood tests are being done. By using a drop of the same blood sample, you will be able to see how much difference (if any) there is between your vet's equipment and your home meter.  Regardless of the brand, most find their glucometer is quite accurate when compared this way.  (Note that some vets, when testing blood glucose and not also other blood values, use a human glucometer instead of their lab equipment.) Mayo Clinic considers a meter to be accurate if it's within 15% of the lab's findings using the same blood sample. 
Reading your glucometerEdit
This chart shows what readings to expect and what to aim for.
In the US, blood glucose is measured in milligrams per deciliter (mg/dL). Almost everywhere else, including the UK, Canada, and Australia, blood glucose is measured in millimoles per liter (mmol/L). You should make sure that your meter “reads” using your country’s system. A blood glucose reported in mg/dL is 18 times larger than the same value reported as mmol/L. For example, a mg/dL reading of 300 would convert to a mmol/L reading of 16.7.
This link  has a calculator to convert numbers between the two systems.
Tip: If a blood glucose value has a decimal component (e.g., 7.7), or is under 25, it is most likely a value being reported in mmol/L.
Factors Which Can Affect ReadingsEdit
Strips not fully inserted into meter
Not enough blood on strip
Batteries low on power
Test strips/Control solutions
|False highs or lows|
Learn the range of your particular meter. The broad values meters measure are from 0-600 mg/dL, but the values are not linear throughout them. Very low or very high readings need to be confirmed; it may be that your meter needs calibration and this is what's causing the abnormal readings. 
In the US, all glucometers designed for use in humans must meet FDA approval standards to be marketed as medical devices. In short, this means that every brand sold must meet at least the minimum FDA requirements. Home glucometers and test strips designed for use in animals are not required to meet any approval standards  before they are placed on the market. There is no requirement that veterinary medical devices be FDA-approved prior to marketing them.
FDA's glucometer standards date back to 1997.  Here are the basics as they were written then; the use of the term "future" would likely apply to all glucometers currently available.
The consensus document expressed the following performance goals: a) "The goal of all future Self Monitoring Blood Glucose (SMBG) systems should be to achieve a variability (system plus user) of 10% at glucose concentrations of 30-400 mg/dL 100% of the time. However, the panel is aware that the accuracy required for clinical management has not been rigorously defined.", b) "With current systems, SMBG measurements should be within 15% of the results of the reference measurements.", c) "Approximately 50-70% of individuals who receive some sort of formal training are capable of obtaining a result within 20% of the reference method; however, performance may deteriorate over time."
Taking Care Of Your MeterEdit
Doing quality control checks of it regularly means being able to depend on its accuracy. See the instructions which came with your brand of meter. An electronic test of the meter means it is working properly; in some models the accuracy can also be checked in this way. Others rely on control solution tests. Some manufacturers include this in their meter kits. The control solution(s) have expiration dates, just as the test strips do. If it is used out of date, the test results may not be accurate. More control solution can be ordered--either from the manufacturer itself or your pharmacy.  Many people with diabetes or their caregivers don't heed this advice and test their glucometers regularly.
Some meters require cleaning, while others do not. Some which need to be cleaned can be cleaned by the owner but others can be cleaned only by the manufacturer. Read the information pamphlet(s) which came with your meter for this information.
Choosing a GlucometerEdit
- Choices by ChildrenWithDiabetes.com
- FDMB members glucometer informal survey
- Hope's glucometer accuracy tests graphed and discussed here and here.
- Article by David Mendosa discussing an upcoming report on a study by US Center for Disease Control (CDC) researchers on the variability of currently marketed glucometers and strips
There seems to be a lot of variance between meters AND their testing strips.
- Good Meter Comparison Chart Diabetes Store
- Graph Comparison--Amount of Blood Sample Needed for All Current US Meters--Childrenwithdiabetes.com
- Meter Testing Times-Childrenwithdiabetes.com
- Test Strip Price Comparisons-2006-Childrenwithdiabetes.com
- ↑ Meter Comparison Page. Hocks.com.
- ↑ Meter Comparison Chart. Focuspharmacy.com.
- ↑ Ease of Use Meter Ratings. Children With Diabetes.
- ↑ What are mg/dl and mmol/l?. Diabetes FAQs.
- ↑ Blood Measurement Units. Abbott Diabetes Care, Australia.
- ↑ Glucometer Information- Possible Causes Of Inaccurate Blood Glucose Readings. US Food and Drug Administration.
- ↑ Prescision Xtra. Moore Medical.
- ↑ Update-Nationwide Alert-Counterfeit Blood Glucose Test Strips. US Food and Drug Administration.
- ↑ LifeScan-OneTouch-Counterfeit Test Strips. LifeScan.
- ↑ Counterfeit Conviction. LifeScan.
- ↑ Meter Comparison Chart. Diabetes Store.
- ↑ Blood Volume Requirements-Meter Test Strips. Children With Diabetes.
- ↑ Computerizing Your Meter. Children With Diabetes.
- ↑ Blood Glucose Meters. Children With Diabetes.
- ↑ New Products. Diabetes In Control.
- ↑ FreeStyle Freedom Glucometer. Medical news Today.
- ↑ FreeStyleFreedom Meter Information. Abbott Diabetes Care.
- ↑ OneTouch Ultra2 Meter Information. LifeScan.
- ↑ 19.0 19.1 What Is Coding?. Bayer Diabetes.
- ↑ Ketone Test Strips. Precision Xtra.
- ↑ New Products 2006. Children With Diabetes.
- ↑ Accu-Chek. Accu-Chek-US.
- ↑ Precision Xtra Meter. Abbott Diabetes Care.
- ↑ Naunheim, Rosanne, et. al. (June 2006). Point of Care Test Identifies Diabetic Ketoacidosis at Triage. Academic Emergency Medicine.
- ↑ Chase, Peter. Value of Testing Blood for Ketones Over Testing Urine. Barbara Davis Diabetes Center.
- ↑ Donohue, PB, Kessler, R., Beattie, TF (October 2006). Exploring the Clinical Utility of Blood Ketone Levels in ER Department Assessment of Pediatric Patients. Emergency Medicine Journal.
- ↑ Byrne,H A, Tieszen,K L, Hollis, Dornan, S T L, New, J P (2000). Evaluation of an Electrochemical Sensor for Measuring Blood Ketones. Diabetes Care 2000.
- ↑ Guerci, Bruno, et. al. (2003). Accuracy of an Electrochemical Sensor for Measuring Capillary Blood Ketones by Fingerstick Samples During Metabolic Deterioration After Continuous Subcutaneous Insulin Infusion Interruption in Type 1 Diabetic Patient. Diabetes Care.
- ↑ Duarte, Ricardo, et. al. (2002). Accuracy of Serum β-Hydroxybutyrate Measurements for the Diagnosis of Diabetic Ketoacidosis in 116 Dogs. Journal of Veterinary Internal Medicine.
- ↑ M. Di Tommaso, G. Aste, F. Rocconi, C. Guglielmini, A. Boari (2009). Evaluation of a Portable Meter to Measure Ketonemia and Comparison with Ketonuria for the Diagnosis of Canine Diabetic Ketoacidosis. Journal of Veterinary Internal Medicine.
- ↑ New/Improved Products-2006. Children With Diabetes.
- ↑ Ketone Testing Strips. Diabetes Self-Management.
- ↑ Precision Xtra Product Outside the US. Medical News Today.
- ↑ Abbott Optimum Xceed. Yorkshire Diabetes.
- ↑ Glucometer Information: Whole Blood vs Plasma Readings. US Food and Drug Administration.
- ↑ Hope & Baby's Meter Accuracy Comparison Charts. Feline Diabetes.
- ↑ EasyGluco. US Diagnostics.
- ↑ Abbott AlphaTrak Website. Abbott Animal Health.
- ↑ 39.0 39.1 Clinical Evaluation of AlphaTrak. Abbott Animal Health.
- ↑ Abbott AlphaTrak Website-1 Footnote at page bottom. Abbott Animal Health.
- ↑ FDMB-AlphaTrak Graph Comparison. Feline Diabetes.
- ↑ FDMB--AlphaTrak Numerical Comparison. Feline Diabetes.
- ↑ Schall, William (2009). Diabetes Mellitus. DVM 360.
- ↑ Brooks, Wendy C.. Diabetes Mellitus Center. Veterinary Partner.
- ↑ Cohen, T. et. al. (2007). Abstract #95-Evaluation of Six Portable Blood Glucose Meters in Dogs-page 30. ACVIM.
- ↑ 46.0 46.1 Greco, Deborah. Ask Dr. Greco. BD Diabetes.
- ↑ Mooney, Carmel T. (2003). Unstable Diabetics-Solving the Problems. WSAVA.
- ↑ Blood Glucose Monitors and Accuracy. Mayo Clinic.
- ↑ Blood Sugar Converter. Children With Diabetes.
- ↑ Glucometer Information-Dehydration & Inaccurate Blood Glucose Results. US Food and Drug Adminsitration.
- ↑ Test Strip Temperature Ranges. Children With Diabetes.
- ↑ Blood Glucose Meter Reference-Listing of Meter Operating Range Temperatures. Diabeteshealth (2005).
- ↑ Glucometer Information- Possible Causes Of Inaccurate Blood Glucose Readings. US Food and Drug Administration.
- ↑ Plastic Medical Devices, Canada. Plastic Medical Devices.
- ↑ UniCheck Generic Test Strips. Tecodiag.com.
- ↑ UniCheck Test strips. AmericaRx.com.
- ↑ Medical Devices-Glucometers. US Food and Drug Administration.
- ↑ Useful Tips to Increase Accuracy and Reduce Errors in Meter Test Results. US Food and Drug Administration.
- ↑ Glucometer Information To Know. DiabeticNews.
- ↑ Regulation of Veterinary Medical Devices. US Food and Drug Administration.
- ↑ Glucometer Standards. US Food and Drug Administration.
- ↑ Glucometer Information--Caring For Your Glucometer. US Food and Drug Administration.
- Evaluation of 6 Portable Blood Glucose Meters in Dogs-page 30, Abstract #95 ACVIM 2008, Oral Presentations
- How home blood and urine tests measure blood glucose Wikipedia