|Humulin ReliOn R|
|R, Neutral by Eli Lilly|
| Action in dogs:
| Also known as: Huminsulin Normal|
Humulin C, Humulin R, Humuline R
Humuline Regular, Humulin Regular
Humulina Regular, Humulin S
Umuline Rapide, Umuline Regular
| Similar to: Insuman Rapid, Winthrop Rapid|
Actrapid, Novolin R, ReliOn/Novolin R
Names of Lilly r-DNA/GE/GM insulins worldwide
|Use and Handling:|
|Shelf Life: 24 months||Type: soluble, clear|
|When Opened: 28 days room temp.|
|In Pen: 28 days room temp.|
| Notes: Protect from light and heat|
Do Not Freeze,
May be used intravenously
Humulin ReliOn R is one of several brands of "Regular" (short-acting) insulin, used for a quick consumption of blood sugar with little delay. ReliOn brand insulin wa formerly made by Novo Nordisk, who had been responsible for producing the ReliOn insulins since 2000.  The ReliOn insulins are still offered in the same types, R, NPH, and 70/30 mix, but they are produced by Eli Lilly and branded as Humulin/ReliOn insulins.  Novolin insulins have NOT been discontinued; these insulins are available as Novolin N, Novolin R, and Novolin 70/30. Only the ReliOn/Novolin branded insulins have been phased out.
It consists of zinc insulin crystals dissolved in clear fluid with no additives to alter its action or speed. 
Other brands with the same action profile include:
- Novolin R 
- Humulin S 
- Huminsulin Normal
- Actrapid 
- Insuman Rapid .
- Winthrop Rapid
While both R/neutral and semilente insulins are considered fast-acting, they differ in a few ways. As above, there's no suspension or buffer  in R/neutral; it's totally dissolved and soluble, meaning it can safely be used intravenously. 
|All Short acting|
|Hypurin Bovine Neutral|
Betasint Bovine Corriente
|Iletin R (No longer produced.)|
Hypurin Vet Neutral (No longer produced.)
Insuvet Neutral (No longer produced.)
|Iletin I R (No longer produced.)|
|Betasint Porcine Corriente|
Hypurin Porcine Neutral
Hypurin Pork Regular
|Pork Actrapid (No longer produced.)|
Iletin II R (No longer produced.)
Leo Neutral (No longer produced.)
|Actrapid, Huminsulin Normal|
Humulin C, Humulin R
Humulin Regular, Humulina Regular
Humuline R, Humuline Regular
Humulin S, Insuman Rapid
Novolin R, Umuline Rapide
Umuline Regular, Winthrop Rapid
Humulin ReliOn R
|R-DNA||ReliOn/Novolin R (No longer produced.)|
- ↑ Insulins. North American Veterinary Conference Clinicians Brief (2006).
- ↑ A Change to ReliOn Insulin. ReliOn.
- ↑ Low Cost Insulin Available through major retailer. Diabetes Health (1 December 2000).
- ↑ Wal-Mart Changes Insulin Partners. Wall Street Journal (22 June 2010).
- ↑ Wal-Mart Press Release (22 June 2010).
- ↑ ReliOn insulins. ReliOn.
- ↑ Humulin R patient leaflet. Eli Lilly.
- ↑ Novolin R Regular Human Insulin. Revolution Health.
- ↑ Patient Information Leaflet-Humulin S. Eli Lilly.
- ↑ Humulin S Prescribing Information.
- ↑ Lilly EU/UK Product Sheet & Time Activity Profiles. Eli Lilly.
- ↑ Patient Information Leaflet-Actrapid. Novo Nordisk.
- ↑ Scientific Discussion-Actrapid. EMEA.
- ↑ Prescribing Novo Insulins.
- ↑ Patient Information Leaflet-Insuman Rapid. Sanofi-Aventis.
- ↑ Prescribing Insuman Insulin.
- ↑ 17.0 17.1 17.2 DeRuiter, Jack. Insulin Preparations-Regular Insulin. Auburn University.
- ↑ Maddison, Jill E.,Page, Stephen W.,Church, David B. (2008). Small Animal Clinical Pharmacology. Saunders Ltd..
- ↑ Deckert, T. (1980). Intermediate-Acting Insulin Preparations: NPH (Isophane) & Lente. Diabetes Care.
Note--in 1980, there were no r-DNA/GE/GM insulins
- ↑ Resource Guide. American Diabetes Association (2005).
- NACDS-Insulin Chart-Page 2
- Leeds NHS UK Insulin Guide
- Insulin therapy for dogs and cats Dowling, Patricia, September 1995, Canadian Veterinary Journal
A discussion of regular/neutral/normal insulins.