Porcine insulin (from pigs) is an exact amino acid match to that of dogs. ^[2]

It differs from human insulin in one position. At B #30 on the B insulin chain, dogs and pigs have Alanine, while people have Threonine. It differs from bovine in two positions, both on the A insulin chain: pigs have Threonine at A #8 while cows have Alanine. At the #10 position on the A insulin chain, pigs have Isoleucine--cows have Valine.

Though this shows CP Pharma's Hypurin pork insulins, ^[3] this information would also apply to Novo's Pork Insulatard, Pork Actrapid, and Pork Mixtard 30. ^[4][5] They can also be applied to compare these to Lilly's former Iletin II R and Iletin II NPH.

These insulins are natural and entirely or partly derived from pork (pig) sources. Only Iletin I R shown on the list below was a mixture of bovine and porcine insulins; it was composed primarily of beef (apx. 85/90%).

This means that they are identical to canine natural insulin, and a bit closer to feline than human insulin is.

Many humans also prefer porcine-based insulins, which are claimed by some to give a clearer warning of impending low blood sugar than the comparable human GE and analog insulins.

Porcine InsulinsEdit

Porcine Insulins
	Short Acting Soluble
R/Neutral	Hypurin Porcine Neutral Hypurin Pork Regular Betasint Porcine Corriente, Maxirapid CHO
R/Neutral	Pork Actrapid (No longer produced.) Iletin II R (No longer produced.) Leo Neutral (No longer produced.)
R/Neutral	Iletin I R Bovine/Porcine insulin. (No longer produced.)
	Short Acting Cloudy
Semilente	Insulinum semilente CHO
Semilente	Novo Semilente MC (No longer produced.)
Semilente	Semitard (No longer produced.)
Semilente	Iletin I Semilente Bovine/Porcine insulin. (No longer produced.)
	Intermediate Acting Non-Mixed
NPH/isophane	Hypurin Porcine Isophane Hypurin Pork NPH Betasint Porcine NPH
NPH/isophane	Iletin II NPH (No longer produced.) Pork Insulatard (No longer produced.) Leo Retard (No longer produced.)
NPH/isophane	Iletin I NPH Bovine/Porcine insulin. (No longer produced.)
Lente	Caninsulin, Vetsulin Betasint Porcine Lente, Lente CHO
Lente	Monotard Pork (No longer produced.) Iletin II Lente (No longer produced.)
Lente	Iletin I Lente Bovine/Porcine insulin (No longer produced.) Lentard MC Bovine/porcine insulin. (No longer produced.)
	Intermediate Acting Mixed
R/Neutral 30% NPH/Isophane 70%	Hypurin Porcine 30/70 Mix
R/Neutral 30% NPH/Isophane 70%	Pork Mixtard 30 (No longer produced.)
R/Neutral 25% NPH/isophane 75%	Rapidtard Bovine/Porcine insulin. (No longer produced.)
	Long Acting
Ultralente	Iletin I Ultralente Bovine/Porcine insulin (No longer produced.)
PZI	PZI Vet Bovine/Porcine insulin (No longer produced.)

See also bovine insulins.

ReferencesEdit

1. ↑ Caninsulin-Product Information. Intervet.
2. ↑ Caninsulin-Product Information. Intervet.
3. ↑ Prescribing Porcine Insulins.
4. ↑ Prescribing Novo Animal Insulins.
5. ↑ Response To Withdrawal of Novo Porcine Insulins. CP/Wockhardt UK.

More InformationEdit

• NACDS-Insulin Chart-Page 2