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Rapidtard

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Rapidtard
R/Neutral/NPH/Isophane Mix by Novo Nordisk
intermediate-acting
Bovine 75% Porcine 25%
U40, U100 Isophane
Action in dogs:
  • onset 0.5-3h,
  • peak 2-10h,
  • duration 4-24h
Line: Novo
Also known as:
Similar to:
Use and Handling:
Shelf Life: 36 months Type: cloudy
When Opened: 6 weeks room temp.
In Pen: N/A
Notes: Protect from light and heat
Do Not Freeze,
Re-suspend
Do not use if product does not re-suspend
Do not use intravenously [1]

Note that some countries have the brand name in U40 strength.

Rapidtard was a 75% Bovine NPH/isophane and 25% Porcine R/neutral/normal mixed insulin made by Novo Nordisk. The name appears to signify the insulin was a combination of Pork Actrapid and Bovine Insulatard, or NPH/isophane insulin. [2]

Mixed insulins cover a wide range as they can be animal origin, r-DNA/GE/GM origin or analog insulins. They can also vary in the fraction (amount or percent) of the two types (R/neutral and NPH/isophane) of insulin used to make a non-analog mix, and in the percentage of fast/rapid-acting analog insulin and slower-acting protamine suspended analog insulin.

For some reason, those in the US choose to list the slower, NPH/isophane based insulin fraction first, such as Humulin or Novolin 70/30. The rest of the world gives the faster insulin top billing and the result is 30/70. Regardless of how this is written, it means that the insulin is made up of 70% NPH/isophane insulin and 30% R/neutral insulin.

The most common mixes are 70/30 (30/70) (non analog) or 75/25 (25/75) (analog). There are no currently-marketed mixes which combine insulins of different origins. Eli Lilly's form of beef/pork Iletin and Novo Nordisk's Lentard were discontinued some time ago. Here are the most common ones that could cause confusion:


ReferencesEdit

  1. Maddison, Jill E.,Page, Stephen W.,Church, David B. (2008). Small Animal Clinical Pharmacology. Saunders Ltd..
  2. Montgomery, DAD. Modern Insulin and Insulin Therapy. Royal Victoria Hospital-Belfast.

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