|R, Neutral by Novo Nordisk|
| Action in dogs:
|Also known as: Actrapid, Novolin R|
| Similar to: Huminsulin Normal, Humulin C|
Humulin R, Humuline R, Humulin Regular
Humulina Regular, Humuline Regular, Humulin S
Humulin ReliOn R, Umuline Rapide
Umuline Regular, Insuman Rapid, Winthrop Rapid
Names of Lilly r-DNA/GE/GM insulins worldwide
|Use and Handling:|
|Shelf Life: 24 months||Type: soluble, clear|
|When Opened: 6 weeks room temp.|
|In Pen: 6 weeks room temp.|
| Notes: Protect from light and heat|
Do Not Freeze,
May be used intravenously
ReliOn brand insulin is no longer made by Novo Nordisk, who had been responsible for producing the ReliOn insulins since 2000.  The ReliOn insulins are still offered in the same types, R, NPH, and 70/30 mix, but they are now produced by Eli Lilly and branded as Humulin/ReliOn insulins.  Novolin insulins have NOT been discontinued; these insulins are available as Novolin N, Novolin R, and Novolin 70/30. Only the ReliOn/Novolin branded insulins have been phased out.
The difference was in the price; the ReliOn branded insulins were cheaper in price but not in quality.
While both R/neutral and semilente insulins are considered fast-acting, they differ in a few ways. As above, there's no suspension or buffer  in R/neutral; it's totally dissolved and soluble, meaning it can safely be used intravenously. 
|All Short acting|
|Hypurin Bovine Neutral|
Betasint Bovine Corriente
|Iletin R (No longer produced.)|
Hypurin Vet Neutral (No longer produced.)
Insuvet Neutral (No longer produced.)
|Iletin I R (No longer produced.)|
|Betasint Porcine Corriente|
Hypurin Porcine Neutral
Hypurin Pork Regular
|Pork Actrapid (No longer produced.)|
Iletin II R (No longer produced.)
Leo Neutral (No longer produced.)
|Actrapid, Huminsulin Normal|
Humulin C, Humulin R
Humulin Regular, Humulina Regular
Humuline R, Humuline Regular
Humulin S, Insuman Rapid
Novolin R, Umuline Rapide
Umuline Regular, Winthrop Rapid
Humulin ReliOn R
|R-DNA||ReliOn/Novolin R (No longer produced.)|
- ↑ Insulins. North American Veterinary Conference Clinicians Brief (2006).
- ↑ A Change to ReliOn Insulin. ReliOn.
- ↑ Low Cost Insulin Available through major retailer. Diabetes Health (1 December 2000).
- ↑ Wal-Mart Changes Insulin Partners (22 June 2010).
- ↑ Wal-Mart Press Release (22 June 2010).
- ↑ ReliOn insulins. ReliOn.
- ↑ ReliOn/Novolin insulins.
- ↑ ReliOn/Novolin R.
- ↑ Patient Information Leaflet-Actrapid. Novo Nordisk.
- ↑ Scientific Discussion-Actrapid. EMEA.
- ↑ Prescribing Novo Insulins.
- ↑ Prescribing Insuman Insulins.
- ↑ Humulin. Eli Lilly.
- ↑ Humulin R Regular Human Insulin. Revolution Health.
- ↑ Patient Information Leaflet-Humulin S. Eli Lilly.
- ↑ Humulin S Prescribing Information.
- ↑ Lilly EU/UK Product Sheet & Time Activity Profiles. Eli Lilly.
- ↑ Patient Information Leaflet-Insuman Rapid. Sanofi-Aventis.
- ↑ DeRuiter, Jack. Insulin Preparations-Regular Insulin. Auburn University.
- ↑ Maddison, Jill E.,Page, Stephen W.,Church, David B. (2008). Small Animal Clinical Pharmacology. Saunders Ltd..
- ↑ DeRuiter, Jack. Insulin Preparations-Lente. Auburn University.
- ↑ Deckert, T. (1980). Intermediate-Acting Insulin Preparations: NPH (Isophane) & Lente. Diabetes Care.
Note--in 1980, there were no r-DNA/GE/GM insulins
- ↑ Resource Guide. American Diabetes Association (2005).
- ↑ DeRuiter, Jack. Insulin Preparations-Lente Insulin. Auburn University.
- NACDS-Insulin Chart-Page 2
- Leeds NHS UK Insulin Guide
- Insulin therapy for dogs and cats Dowling, Patricia, September 1995, Canadian Veterinary Journal
A discussion of regular/neutral/normal insulins.